Pharmaceuticals are useful tools for mechanism of action studies in many ways. Besides being enzyme inhibitors, receptor agonists or antagonists, channel blockers, neurotransmitters themselves, they are used to compare and define other emerging compounds for their prospective applications.
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Product Name: Irinotecan hydrochloride trihydrate, 98 Order number: 50P987783 CAS: 136572-09-3 Purity: >=95% Appearance: solid MF: C33H45ClN4O9 MW: 677.192 MP: 250-256 (dec.) oC Description: This compound is an analog of camptothecin. Irinotecan competes for binding to DNA strand to prevent formation of topoisomerase I-DNA complex, thereby causing double-strand DNA breakage. |
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Product Name: Erlotinib Order number: 100779 CAS: 183319-69-9 Purity: >=95% Appearance: solid MF: C22H24ClN3O4 MW: 429.901 MP: 228-230 (M.I.) oC Description: It is in the tyrosine kinase receptor inhibitor class of medications. |
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Product Name: SB203580 Order number: 101038 CAS: 152121-47-6 Purity: >=95% Appearance: solid MF: C21H16FN3OS MW: 377.437 MP: n.a. oC Description: This substance is a highly selective inhibitor of p38 MAP kinase, competing with ATP for binding to p38. |
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Product Name: Etoposide phosphate Order number: 212082 CAS: 117091-64-2 Purity: 98(HPLC)% Appearance: n.a. MF: C29H33O16P MW: 668.5 MP: n.a. oC Description: It inhibits DNA synthesis. |