We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N2-iBu-5'-O-DMT-2'-OMe-G-CE Order number: 204731 CAS: 150780-67-9 Purity: 98% Appearance: solid MF: C45H56N7O9P MW: 869.96 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: N4-Ac-5'-O-DMT-2'-OMe-C-CE Order number: 204732 CAS: 199593-09-4 Purity: 98% Appearance: solid MF: C42H52N5O9P MW: 801.88 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: N4-Ac-5'-O-DMT-2'-fluoro-dC-CE Order number: 204735 CAS: 159414-99-0 Purity: 98% Appearance: solid MF: C41H49FN5O8P MW: 789.84 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: N2-iBu-5'-O-DMT-2'-fluoro-dG-CE Order number: 204736 CAS: 144089-97-4 Purity: 98% Appearance: solid MF: C44H53FN7O8P MW: 857.92 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: 5'-O-DMT-2'-fluoro-dU-CE Order number: 204737 CAS: 146954-75-8 Purity: 98% Appearance: solid MF: C39H46FN4O8P MW: 748.79 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-dU-CE Phosphoramidite Order number: 204738 CAS: 109389-30-2 Purity: 98% Appearance: solid MF: C39H47N4O8P MW: 730.80 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |