Pharmaceuticals are useful tools for mechanism of action studies in many ways. Beside being enzyme inhibitors, receptor agonists or antagonists, channel blockers, neurotransmitters themselves, they are used to compare and define other emerging compounds for their prospective applications.
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Product Name: Tramadol hydrochloride Order number: 100970 CAS: 36282-47-0 Purity: >=95% Appearance: solid MF: C16H26ClNO2 MW: 299.839 MP: 180-181 (M.I.) oC Description: Tramadol inhibits the reuptake of the natural neurotransmitters norepinephrine (noradrenaline) and serotonin, and also binds weakly to mu-opioid receptors, blocking the transmission of pain signals to the brain. |
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Product Name: Hydrocortisone-17-valerate Order number: 100989 CAS: 57524-89-7 Purity: >=95% Appearance: solid MF: C26H38O6 MW: 446.584 MP: n.a. oC Description: Hydrocortisone binds to the cytosolic glucocorticoid receptor. |
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Product Name: Hydrocortisone acetate Order number: 101009 CAS: 50-03-3 Purity: >=95% Appearance: solid MF: C23H32O6 MW: 404.503 MP: n.a. oC Description: This substance inhibits accumulation of inflammatory cells at inflammation sites, phagocytosis, lysosomal enzyme release and synthesis, and release of mediators of inflammation. |
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Product Name: 16a-Hydroxyprednisolone Order number: RT-R06-403/R07-410 CAS: 13951-70-7 Purity: >=95% Appearance: solid MF: C21H28O6 MW: 376.449 MP: n.a. oC Description: This substance inhibits phospholipase A2, which decreases the formation of arachidonic acid derivatives, and it inhibits NF-Kappa B and other inflammatory transcription factors; further it promotes anti-inflammatory genes like interleukin-10. |
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Product Name: D,L-Dihydroorotic acid Order number: RT-R1-155 CAS: 6202-10--4 Purity: >=95% Appearance: solid MF: C5H6N2O4 MW: 158.113 MP: n.a. oC Description: This is a racemic mixture of L and D isomers of dihydroorotic acid. |
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Product Name: L-Dihydroorotic acid Order number: RT-R1-168 CAS: 5988-19-2 Purity: >=95% Appearance: solid MF: C5H6N2O4 MW: 158.113 MP: 254 oC Description: L-Dihydroorotic acid universally exists in living organisms. It is implicated in the metabolic disorder called the beta-ureidopropionase deficiency pathway. It is a substrate of dihydroorotate dehydrogenase, the inhibition of which is implied in treating autoimmune diseases. |