Research Pharmaceuticals and Intermediates

Pharmaceuticals are useful tools for mechanism of action studies in many ways. Beside being enzyme inhibitors, receptor agonists or antagonists, channel blockers, neurotransmitters themselves, they are used to compare and define other emerging compounds for their prospective applications.

  • Group 1
  • Group 2
  • Group 3
  • Group 4
  • Group 5
  • Group 6
  • Others
  • Group 2

    Structure Details
    Product Name: Docetaxel
    Order number: 100245
    CAS: 114977-28-5
    Purity: >=95%
    Appearance: solid
    MF: C43H53NO14
    MW: 807.89
    MP: 232 (M.I.) oC

    This inhibitor of microtubular deploymerization also interacts with bcl-2/bcl-xL gene expression.
    Product Name: Gefitinib
    Order number: 100356
    CAS: 184475-35-2
    Purity: >=95%
    Appearance: solid
    MF: C22H24ClFN4O3
    MW: 446.907
    MP: 119-120(M.I.) oC

    This EGFR inhibitor inhibits autophosphorylation and downstream singaling pathways, leading induction of apoptosis.
    Product Name: Methotrexate
    Order number: 100465
    CAS: 59-05-2
    Purity: >=95%
    Appearance: solid
    MF: C20H22N8O5
    MW: 454.447
    MP: 185-204 (M.I.) oC

    This folate antagonist inhibits DHFR and interferes with DNA synthesis, repair, and cellular replication.
    Product Name: Etoricoxib
    Order number: 100556
    CAS: 202409-33-4
    Purity: >=95%
    Appearance: solid
    MF: C18H15ClN2O2S
    MW: 358.84
    MP: 127-128 (M.I.) oC

    This compound inhibits cyclo-oxygenase-2 (COX-2) enzyme.
    Product Name: Vandetanib
    Order number: 100787
    CAS: 443913-73-3
    Purity: >=95%
    Appearance: solid
    MF: C22H24BrFN4O2
    MW: 475.362
    MP: 235 oC

    This compound inhibits VEGFR-2 and epidermal growth factor receptor (EGFR) tyrosine kinase activity.
    Product Name: N-(3-Benzoylamido-6-methylphenyl)-4-(3-pyridyl)-2-pyrimidine amine (CGP-53716)
    Order number: RT-BS-027
    CAS: 152459-94-4
    Purity: >=95%
    Appearance: solid
    MF: C23H19N5O
    MW: 381.439
    MP: n.a. oC

    This substance inhibits protein-tyrosine kinase and exhibits selectivity for the PDGF receptor in vitro and in the cell.