Amino Acids and Nucleosides

We offer Fmoc-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and, at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Modified Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Other Nucleosides & Intermediates
  • Structure Details
    Product Name: 2-Amino-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
    Order number: 201164
    CAS: 7355-55-7
    Purity: >=95%
    Appearance: solid
    MF: C6H6N4O
    MW: 150.141
    MP: n.a. oC

    Description:
    Deazapurine base for synthesizing nucleoside.
    Product Name: (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-2-methylhept-6-enoic acid
    Order number: 201167
    CAS: 288617-73-2
    Purity: >=95%
    Appearance: solid
    MF: C23H25NO4
    MW: 379.456
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.
    Product Name: 8-Azidoadenosine
    Order number: 201183
    CAS: 4372-67-2
    Purity: >=95%
    Appearance: solid
    MF: C10H12N8O4
    MW: 308.258
    MP: n.a. oC

    Description:
    This is a nucleoside for antiviral activity and potential labeling purpose via click chemistry.
    Product Name: 8-Bromoadenosine
    Order number: 201184
    CAS: 2946-39-6
    Purity: >=95%
    Appearance: solid
    MF: C10H12BrN5O4
    MW: 346.141
    MP: n.a. oC

    Description:
    This is a nucleoside for antiviral activity and potential labeling purpose via cross coupling chemistry.
    Product Name: 2',3'-Dideoxyuridine
    Order number: 201284
    CAS: 5983--09-5
    Purity: >=95%
    Appearance: solid
    MF: C9H12N2O4
    MW: 212.205
    MP: n.a. oC

    Description:
    The dideoxyuridine nucleosides have found broad antiviral activities.
    Product Name: 2'-Azido-2'-deoxyuridine
    Order number: 201288
    CAS: 26929-65-7
    Purity: >=95%
    Appearance: solid
    MF: C9H11N5O5
    MW: 269.217
    MP: n.a. oC

    Description:
    This is a nucleoside for antiviral activity and potential labeling purpose via click chemistry.