We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Order number: 211372 CAS: 129451-75-8 Purity: 97% Appearance: WHITE CRYSTALLINE POWDER MF: C53H66N7O8PSi MW: 988.2 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Order number: 211380 CAS: 136834-22-5 Purity: 98% Appearance: SOLID MF: C47H51FN7O7P MW: 875.9 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: Uridine 5'-(trihydrogen diphosphate), P'-?-D-galactopyranosyl ester, sodium salt (1:2) Order number: 211383 CAS: 137868-52-1 Purity: 98% Appearance: SOLID MF: C15H22N2Na2O17P2 MW: 610.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate hydrate(2:1:x) Order number: 211392 CAS: 146877-92-1 Purity: 95% Appearance: SOLID MF: C10H14N5Na2O8P MW: 409.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: D-Ribofuranose, 1,5-bis(dihydrogen phosphate) Order number: 211393 CAS: 14689-84-0 Purity: 90% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Order number: 211396 CAS: 147201-04-5 Purity: 98% Appearance: LIGHT YELLOW CRYSTALLINE POWDER MF: C50H68N7O9PSi MW: 970.2 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |