Amino Acids and Nucleosides

We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

HNA Precursors

Structure	Details
	Product Name: 1-[2,5-Anhydro-4-C-(hydroxymethyl)-a-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione Order number: 204505 CAS: 705967-67-5 Purity: >=95% Appearance: solid MF: C18H19N5O4 MW: 369.381 MP: n.a. oC Description: This is a chemical precursor of hexitol nucleic acid (HNA) contains the standard nucleoside bases, but with a phosphorylated 1',5'-anhydrohexitol backbone. HNA duplexes are more stable and found in antisense and siRNA applications. Login to check availability and price information.
	Product Name: 2-(6-Amino-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol Order number: 204506 CAS: 705967-83-5 Purity: >=95% Appearance: solid MF: C18H19N5O5 MW: 385.38 MP: n.a. oC Description: This is a chemical precursor of hexitol nucleic acid (HNA) contains the standard nucleoside bases, but with a phosphorylated 1',5'-anhydrohexitol backbone. HNA duplexes are more stable and found in antisense and siRNA applications. Login to check availability and price information.
	Product Name: 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol Order number: 204507 CAS: 401906-98-7 Purity: >=95% Appearance: solid MF: C17H18N2O6 MW: 346.339 MP: n.a. oC Description: This is a chemical precursor of hexitol nucleic acid (HNA) contains the standard nucleoside bases, but with a phosphorylated 1',5'-anhydrohexitol backbone. HNA duplexes are more stable and found in antisense and siRNA applications. Login to check availability and price information.
	Product Name: 1,5-Anhydro-2-deoxy-2-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-4,6-O-[(R)-phenylmethylene]-D-altritol Order number: 204508 CAS: 937031-51-1 Purity: >=95% Appearance: solid MF: C17H19N3O5 MW: 345.355 MP: n.a. oC Description: This is a chemical precursor of hexitol nucleic acid (HNA) contains the standard nucleoside bases, but with a phosphorylated 1',5'-anhydrohexitol backbone. HNA duplexes are more stable and found in antisense and siRNA applications. Login to check availability and price information.
	Product Name: 2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol Order number: 204509 CAS: 705967-79-9 Purity: >=95% Appearance: solid MF: C18H18ClN5O4 MW: 403.823 MP: n.a. oC Description: This is a chemical precursor of hexitol nucleic acid (HNA) contains the standard nucleoside bases, but with a phosphorylated 1',5'-anhydrohexitol backbone. HNA duplexes are more stable and found in antisense and siRNA applications. Login to check availability and price information.
	Product Name: 2-(2-Amino-6-chloro-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol Order number: 204510 CAS: 937031-52-2 Purity: >=95% Appearance: solid MF: C18H21N3O5 MW: 359.382 MP: n.a. oC Description: This is a chemical precursor of hexitol nucleic acid (HNA) contains the standard nucleoside bases, but with a phosphorylated 1',5'-anhydrohexitol backbone. HNA duplexes are more stable and found in antisense and siRNA applications. Login to check availability and price information.