Amino Acids and Nucleosides

We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

Morpholino Nucleosides

Structure	Details
	Product Name: 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-2,4(1H,3H)-pyrimidinedione Order number: 204544 CAS: 109205-43-8 Purity: >=95% Appearance: solid MF: C9H13N3O4 MW: 227.22 MP: n.a. oC Description: Morpholino nucleosides have been seen in hybrid dinucleotides to show potent activity against poly(ADP-ribose)polymerases-1, 2. PARP inhibitors can prevent cancer cells from repairing their DNA once t Login to check availability and price information.
	Product Name: 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione Order number: 204545 CAS: 179073-10-0 Purity: >=95% Appearance: solid MF: C10H15N3O4 MW: 241.247 MP: n.a. oC Description: Morpholino nucleosides have been seen in hybrid dinucleotides to show potent activity against poly(ADP-ribose)polymerases-1, 2. PARP inhibitors can prevent cancer cells from repairing their DNA once t Login to check availability and price information.
	Product Name: N-[1,2-Dihydro-1-[(2R,6S)-6-(hydroxymethyl)-2-morpholinyl]-2-oxo-4-pyrimidinyl]-benzamide Order number: 204546 CAS: 125455-77-8 Purity: >=95% Appearance: solid MF: C16H18N4O4 MW: 330.344 MP: n.a. oC Description: Morpholino nucleosides have been seen in hybrid dinucleotides to show potent activity against poly(ADP-ribose)polymerases-1, 2. PARP inhibitors can prevent cancer cells from repairing their DNA once t Login to check availability and price information.
	Product Name: N-[9-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-9H-purin-6-yl]-benzamide Order number: 204547 CAS: 139290-78-1 Purity: >=95% Appearance: solid MF: C17H18N6O3 MW: 354.37 MP: n.a. oC Description: Morpholino nucleosides have been seen in hybrid dinucleotides to show potent activity against poly(ADP-ribose)polymerases-1, 2. PARP inhibitors can prevent cancer cells from repairing their DNA once t Login to check availability and price information.
	Product Name: N-[6,9-Dihydro-9-[(2R,6S)-6-(hydroxymethyl)-2-morpholinyl]-6-oxo-1H-purin-2-yl]-2-methyl-propanamide Order number: 204548 CAS: 956139-23-4 Purity: >=95% Appearance: solid MF: C14H20N6O4 MW: 336.352 MP: n.a. oC Description: Morpholino nucleosides have been seen in hybrid dinucleotides to show potent activity against poly(ADP-ribose)polymerases-1, 2. PARP inhibitors can prevent cancer cells from repairing their DNA once t Login to check availability and price information.