Amino Acids and Nucleosides

We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

Other Unnatural Amino Acids

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Structure	Details
	Product Name: D-Arg(Me, Me)-OH (symmetrical) Order number: 204484 CAS: 190784-53-5 Purity: >=95% Appearance: solid MF: C8H18N4O2 MW: 202.258 MP: n.a. oC Description: This Fmoc-protected solid-phase amenable amino acid carries a protonatable side chain that may be useful for tuning cellular permeability of peptides. Login to check availability and price information.
	Product Name: Fmoc-D-Arg(Me, Me)-OH (asymmetrical) Order number: 204486 CAS: N/A Purity: >=95% Appearance: solid MF: C23H28N4O4 MW: 424.501 MP: n.a. oC Description: This Fmoc-protected solid-phase amenable amino acid carries a protonatable side chain that may be useful for tuning cellular permeability of peptides. Login to check availability and price information.
	Product Name: Fmoc-Lys(Me2)-OH hydrochloride salt Order number: 204487 CAS: 252049-10-8 Purity: >=95% Appearance: solid MF: C23H28N2O4 MW: 396.487 MP: n.a. oC Description: This Fmoc-protected solid-phase amenable amino acid carries a protonatable side chain that may be useful for tuning cellular permeability of peptides. Login to check availability and price information.
	Product Name: Fmoc-Lys(IVDDE)-OH Order number: 204488 CAS: 204777-78-6 Purity: >=95% Appearance: solid MF: C34H42N2O6 MW: 574.718 MP: n.a. oC Description: This Fmoc and DDE orthogonally protected solid-phase amenable amino acid carries a protonatable side chain that may be useful for tuning cellular permeability of the peptides. Once freed, the epsilon amine may be used also to form lactam to enhance helicity. Login to check availability and price information.
	Product Name: Fmoc-STA-OH Order number: 204648 CAS: 158257-40-0 Purity: >=95% Appearance: solid MF: C23H27NO5 MW: 397.471 MP: 92-94 oC Description: This Fmoc-protected solid-phase amenable amino acid is a key repeating unit of peptid,e pepstatin, that inhibits cathepsin E. Login to check availability and price information.
	Product Name: (S)-2-Amino-N,3,3-trimethylbutanamide Order number: 204649 CAS: 89226-12-0 Purity: >=95% Appearance: solid MF: C7H16N2O MW: 144.218 MP: n.a. oC Description: Steric amino acid to form stable peptide bond against proteolytic breakdown. Login to check availability and price information.

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