Amino Acids and Nucleosides

We offer FMOC-protected unnatural amino acids for synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

We offer nucleosides with modifications at the pyrimidine or purine base, such as 6- Thioguanine, 7-Deazaadenine, 7-Deazaguanine, 8-Azidoadenine, 8-Bromoinosine and 8- Iodoadenine, and at the sugar such as 5'-Azido-5'-deoxythymidine, 2'-Azido-2'-deoxyuridine and 2'-Azido-2'-deoxy-5-methyl uridine.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Modified Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Other Nucleosides & Intermediates
  • Amino Acids for Stapled Peptides

    Structure Details
    Product Name: (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-2-methylhept-6-enoic acid
    Order number: 201167
    CAS: 288617-73-2
    Purity: >=95%
    Appearance: solid
    MF: C23H25NO4
    MW: 379.456
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.
    Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
    Order number: 201306
    CAS: 288617-71-0
    Purity: >=95%
    Appearance: solid
    MF: C21H21NO4
    MW: 351.402
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.
    Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
    Order number: 201307
    CAS: 288617-76-5
    Purity: >=95%
    Appearance: solid
    MF: C21H21NO4
    MW: 351.402
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.
    Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-6-heptenoic acid
    Order number: 201308
    CAS: 288617-77-6
    Purity: >=95%
    Appearance: solid
    MF: C23H25NO4
    MW: 379.456
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.
    Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-9-decenoic acid
    Order number: 201309
    CAS: 288617-75-4
    Purity: >=95%
    Appearance: solid
    MF: C26H31NO4
    MW: 421.537
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.
    Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-9-decenoic acid
    Order number: 201310
    CAS: 945212-26-0
    Purity: >=95%
    Appearance: solid
    MF: C26H31NO4
    MW: 421.537
    MP: n.a. oC

    Description:
    The alkenyl side chain of this product, Fmoc-protected and solid-phase amenable, can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process.