We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Order number: 211399 CAS: 1445905-51-0 Purity: 98% Appearance: WHITE POWDER MF: C50H68N7O9PSi MW: 970.2 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: 5'-Inosinic acid, 2'-deoxy-, sodium salt (1:2) Order number: 211404 CAS: 14999-52-1 Purity: 98% Appearance: SOLID MF: C10H11N4Na2O7P MW: 376.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine 5'-(trihydrogen diphosphate), sodium salt (1:2) Order number: 211420 CAS: 16178-48-6 Purity: 97% Appearance: SOLID MF: C10H13N5Na2O10P2 MW: 471.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: D-Ribose, 5-(dihydrogen phosphate), sodium salt (1:2) Order number: 211431 CAS: 18265-46-8 Purity: 85% Appearance: SOLID MF: C5H9Na2O8P MW: 274.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy- Order number: 211436 CAS: 2056-98-6 Purity: ?98% Appearance: n.a. MF: C9H16N3O13P3 MW: 467.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: ADENOSINE 5'-DIPHOSPHATE SODIUM SALT Order number: 211438 CAS: 20398-34-9 Purity: 90% Appearance: SOLID MF: C10H12N5Na3O10P2 MW: 493.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |