We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine 5'-(trihydrogen diphosphate), P'?5'-ester with 3-(aminocarbonyl)-1-?-D-ribofuranosylpyridinium, inner salt, sodium salt (1:1) Order number: 211446 CAS: 20111-18-6 Purity: 95% Appearance: SOLID MF: C21H27N7NaO14P2 MW: 686.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy- Order number: 211447 CAS: 1927-31-7 Purity: 97% Appearance: SOLID MF: C10H16N5O12P3 MW: 491.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 5'-Inosinic acid, sodium salt, hydrate (1:2:8) Order number: 211451 CAS: 20813-76-7 Purity: 98% Appearance: SOLID MF: C10H27N4Na2O16P MW: 536.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-Cytidylic acid, 2'-deoxy-5-methyl- Order number: 211464 CAS: 2498-41-1 Purity: 95% Appearance: n.a. MF: C10H16N3O7P MW: 321.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Uridine 5'-(trihydrogen diphosphate), sodium salt (1:2) Order number: 211476 CAS: 27821-45-0 Purity: 96% Appearance: WHITE POWDER MF: C9H12N2Na2O13P2 MW: 464.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: URIDINE-13C9, 15N2-5 TRIPHOSPHATE SODI U Order number: 211478 CAS: 285978-18-9 Purity: ?98% Appearance: SOLID MF: C9H13N2Na2O15P3 MW: 528.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |