Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Nucleoside Phosphoramidites and Nucleotides
  • Nucleoside Phosphoramidites and Nucleotides

    Structure Details
    Product Name: 5'-Adenylic acid, 2'-deoxy-, sodium salt (1:2)
    Order number: 211480
    CAS: 2922-74-9
    Purity: 98%
    Appearance: SOLID
    MF: C10H12N5Na2O6P
    MW: 375.2
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.
    Product Name: Adenosine 5'-(trihydrogen diphosphate), trilithium salt (9CI)
    Order number: 211489
    CAS: 31008-64-7
    Purity: 98%
    Appearance: SOLID
    MF: C10H15Li2N5O10P2
    MW: 441.1
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.
    Product Name: 5'-Uridylic acid, sodium salt (1:1)
    Order number: 211490
    CAS: 3106-18-1
    Purity: 95%
    Appearance: n.a.
    MF: C9H12N2NaO9P
    MW: 346.2
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.
    Product Name: 5'-Inosinic acid, homopolymer
    Order number: 211491
    CAS: 30918-54-8
    Purity: 90%
    Appearance: WHITE POWDER
    MF: C10H13N4O8P
    MW: 348.2
    MP: n.a. oC

    Description:
    Useful building block for nucleoside and nucleotide chemistry
    Product Name: Polycytidylic acid
    Order number: 211493
    CAS: 30811-80-4
    Purity: Assay?85.0%
    Appearance: SOLID
    MF:
    MW:
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.
    Product Name: beta-Nicotinamide Adenine Dinucleotide
    Order number: 211507
    CAS: 53-84-9
    Purity: 98%
    Appearance: WHITE POWDER
    MF: C21H27N7O14P2
    MW: 663.4
    MP: n.a. oC

    Description:
    This is a useful material for nucleotide chemistry and biology.