We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-Xanthylic acid, sodium salt (1:2) Order number: 211515 CAS: 25899-70-1 Purity: 98% Appearance: SOLID MF: C10H11N4Na2O9P MW: 408.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 8-Bromo-cAMP sodium salt Order number: 211520 CAS: 76939-46-3 Purity: 99% Appearance: OFF-WHITE POWDER MF: C10H10BrN5NaO6P MW: 430.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine 5'-monophosphate disodium salt Order number: 211527 CAS: 4578-31-8 Purity: 95% Appearance: SOLID MF: C10H12N5Na2O7P MW: 391.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-Adenylic acid, hydrate (1:1) Order number: 211533 CAS: 18422-05-4 Purity: 95% Appearance: SOLID MF: C10H16N5O8P MW: 365.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ?-Nicotinamide mononucleotide Order number: 211534 CAS: 1094-61-7 Purity: 98% Appearance: SOLID MF: C11H15N2O8P MW: 334.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt Order number: 211535 CAS: 16980-89-5 Purity: ?97 (HPLC)% Appearance: SOLID MF: C18H23N5NaO8P MW: 491.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |