We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Barium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl phosphate Order number: 211586 CAS: 3249-92-1 Purity: 95% Appearance: SOLID MF: C10H11BaN4O8P MW: 483.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Inosine 5'-monophosphate disodium salt hydrate Order number: 211591 CAS: 352195-40-5 Purity: 97% Appearance: SOLID MF: C10H13N4Na2O9P MW: 410.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Cytidine 5'-monophosphate disodium salt Order number: 211599 CAS: 6757-06-8 Purity: 98% Appearance: SOLID MF: C9H12N3Na2O8P MW: 367.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Disodium 5'-Inosinate Order number: 211602 CAS: 4691-65-0 Purity: ?97% Appearance: SOLID MF: C10H11N4Na2O8P MW: 392.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Ribonucleic Acid Order number: 211614 CAS: 63231-63-0 Purity: 87% Appearance: SOLID MF: MW: MP: n.a. oC Description: RNA |
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Product Name: Cytidine 5?-triphosphate disodium salt Order number: 211616 CAS: 81012-87-5 Purity: 99% Appearance: SOLID MF: C9H18N3Na2O16P3 MW: 563.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |