We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: ?, ?-Methyleneadenosine 5'-triphosphate disodium salt Order number: 211647 CAS: 7414-56-4 Purity: 97% Appearance: SOLID MF: C11H18N5Na2O12P3 MW: 551.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Guanosine 3',5'-monophosphate Order number: 211648 CAS: 7665-99-8 Purity: ?98% Appearance: SOLID MF: C10H12N5O7P MW: 345.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: alpha-nicotinamide adenine dinucleotide,alpha-diphosphopyri Order number: 211651 CAS: 7298-93-3 Purity: from Saccharomyces cerevisiae, ?1 -isomer, ?95% Appearance: n.a. MF: C21H27N7O14P2 MW: 663.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt Order number: 211652 CAS: 94825-44-2 Purity: n.a.% Appearance: SOLID MF: C10H12Li4N5O13P3S MW: 563 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Adenosine 5'-[?-thio]triphosphate tetralithium salt Order number: 211663 CAS: 93839-89-5 Purity: ?80% Appearance: SOLID MF: C10H14Li4N5O5P2 MW: 374 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine Amine Congener Order number: 211665 CAS: 96760-69-9 Purity: 98% Appearance: GREY WHITE SOLID POWDER MF: C28H32N8O6 MW: 576.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |