We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 3'-Adenylicacid, disodium salt (8CI,9CI) Order number: 211673 CAS: 4958-39-8 Purity: ? 98 (HPLC)% Appearance: n.a. MF: C10H12N5O7P-- MW: 345.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-Uridylic acid,5-bromo- Order number: 211680 CAS: 2149-79-3 Purity: 98% Appearance: n.a. MF: C9H10BrN2O9P-- MW: 401.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate Order number: 211681 CAS: 42155-08-8 Purity: 98% Appearance: WHITE POWDER MF: C9H11N2Na2O8P MW: 352.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: adenosine 2':3'-cyclic monophosphate sodium salt Order number: 211683 CAS: 37063-35-7 Purity: n.a.% Appearance: SOLID MF: C10H11N5NaO6P MW: 351.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Inosine-5'-triphosphate trisodium salt Order number: 211687 CAS: 35908-31-7 Purity: 96% Appearance: WHITE POWDER MF: C10H12N4Na3O14P3 MW: 574.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 2 -O-Methyl-rA(N-Bz)phosphoramidite Order number: 211702 CAS: 110782-31-5 Purity: 98% Appearance: OFF-WHITE POWDER? MF: C48H54N7O8P MW: 888 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |