We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2'-Deoxyguanosine 3'-monophosphate sodium salt Order number: 211711 CAS: 102814-03-9 Purity: n.a.% Appearance: n.a. MF: C10H14N5NaO7P MW: 370.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Thymidine 5'-diphosphate sodium salt Order number: 211714 CAS: 108322-12-9 Purity: ?96 (HPLC)% Appearance: SOLID MF: C10H13N2Na2O11P2- MW: 445.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Uridine-5'-diphosphoglucose, disodium salt Order number: 211715 CAS: 117756-22-6 Purity: 95% Appearance: SOLID MF: C15H22N2Na2O17P2 MW: 610.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ?,?-Methyleneguanosine 5'-triphosphate sodium salt Order number: 211717 CAS: 10470-57-2 Purity: ?95% Appearance: n.a. MF: C11H18N5NaO13P3 MW: 544.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Flavin Adenine Dinucleotide disodium salt hydrate Order number: 211725 CAS: 84366-81-4 Purity: 97% Appearance: SOLID MF: C27H31N9Na2O15P2 MW: 829.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE Order number: 211728 CAS: 102029-93-6 Purity: 92% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |