We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: adenosine5 -diphosphate,monosodiumsaltdihydrate Order number: 211747 CAS: 1172-42-5 Purity: 98% Appearance: n.a. MF: C10H14N5NaO10P2 MW: 449.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Order number: 211748 CAS: 110764-79-9 Purity: 98% Appearance: SOLID MF: C40H49N4O9P MW: 760.8 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: ADENOSINE 3'-PHOSPHATE 5'-PHOSPHOSULFATE LITHIUM Order number: 211751 CAS: 109434-21-1 Purity: n.a.% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ADENOSINE5'-MONOPHOSPHATESODIUMSALT Order number: 211755 CAS: 13474-03-8 Purity: 98% Appearance: SOLID MF: C10H14N5NaO7P MW: 370.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-O-(4,4-Dimethoxytrityl)-N-[[4-(tert-butyl)phenoxy]acetyl]-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Order number: 211783 CAS: 179486-26-1 Purity: 95% Appearance: n.a. MF: C52H64N5O10P MW: 950.1 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: FLAVIN ADENINE DINUCLEOTIDE Order number: 211785 CAS: 146-14-5 Purity: 98% Appearance: SOLID MF: C27H33N9O15P2 MW: 785.5 MP: n.a. oC Description: Redox-active coenzyme |