We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: CYTIDINE 5'-MONOPHOSPHO-N- Order number: 211800 CAS: 3063-71-6 Purity: 98% Appearance: SOLID MF: C20H31N4O16P MW: 614.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenylyl Imidodiphosphate Order number: 211814 CAS: 25612-73-1 Purity: ?93 (HPLC), powder% Appearance: n.a. MF: C10H15Li4N6O13P3 MW: 547.9 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: THIONICOTINAMIDE ADENINE DINUCLEOTIDE Order number: 211821 CAS: 4090-29-3 Purity: 95.0(HPLC)% Appearance: SOLID MF: C21H33N7O13P2S MW: 685.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 8-CHLORO-CAMP Order number: 211823 CAS: 41941-56-4 Purity: 98% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3'-UMP NA Order number: 211849 CAS: 35170-03-7 Purity: n.a.% Appearance: SOLID MF: C9H11N2Na2O9P MW: 368.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Order number: 211858 CAS: 51116-01-9 Purity: 98% Appearance: n.a. MF: C10H10BrN5NaO7P MW: 446.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |