We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: c-di-AMP Order number: 211866 CAS: 54447-84-6 Purity: 98% Appearance: n.a. MF: C20H24N10O12P2 MW: 658.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: GUANOSINE 5'-DIPHOSPHATE SODIUM SALT Order number: 211879 CAS: 43139-22-6 Purity: 97% Appearance: SOLID MF: C10H12N5Na3O11P2 MW: 509.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: UDPGA TRISODIUM SALT Order number: 211909 CAS: 63700-19-6 Purity: 98% Appearance: SOLID MF: C15H19N2Na3O18P2 MW: 646.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: CYTIDINE 5'-TRIPHOSPHATE DISODIUM Order number: 211912 CAS: 652154-13-7 Purity: n.a.% Appearance: n.a. MF: C9H18N3Na2O15P3 MW: 547.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: bis(3',5')-cyclic diguanylic acid Order number: 211917 CAS: 61093-23-0 Purity: ?98% Appearance: n.a. MF: C20H24N10O14P2 MW: 690.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ADENYLYL-IMIDODIPHOSPHATE, TETRALITHIUM SALT Order number: 211931 CAS: 72957-42-7 Purity: ?90(HPLC)% Appearance: SOLID MF: C10H13Li4N6O12P3 MW: 529.9 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |