We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2'-Deoxythymidine-5'-triphosphate (dTTP)? trisodium salt? dihydrate Order number: 211994 CAS: 18423-43-3 Purity: 97% Appearance: SOLID MF: C10H16N2NaO14P3 MW: 504.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: ?-Nicotinamide adenine dinucleotide phosphate disodium salt Order number: 212002 CAS: 24292-60-2 Purity: 99% Appearance: SOLID MF: C21H26N7Na2O17P3 MW: 787.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine5'-(tetrahydrogen triphosphate), disodium salt, hydrate (8CI,9CI) Order number: 212011 CAS: 34369-07-8 Purity: 98% Appearance: WHITE POWDER MF: C10H16N5Na2O14P3 MW: 569.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 5'-Thymidylic acid, disodium salt Order number: 212012 CAS: 33430-62-5 Purity: 95% Appearance: SOLID MF: C10H13N2Na2O8P MW: 366.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate hydrate Order number: 212018 CAS: 402846-49-5 Purity: 95% Appearance: SOLID MF: C10H14N5Na2O8P MW: 409.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Guanosine, cyclic 3',5'-(hydrogen phosphate), monosodium salt Order number: 212020 CAS: 40732-48-7 Purity: 98% Appearance: SOLID MF: C10H11N5NaO7P MW: 367.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |