We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: ?-Nicotinamide adenine dinucleotide phosphate Order number: 212030 CAS: 53-59-8 Purity: 95% Appearance: SOLID MF: C21H28N7O17P3 MW: 743.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine 5'-(tetrahydrogen triphosphate), disodium salt, trihydrate Order number: 212035 CAS: 51963-61-2 Purity: 99% Appearance: SOLID MF: C10H20N5Na2O16P3 MW: 605.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: Adenosine 5'-diphosphate Order number: 212037 CAS: 58-64-0 Purity: 97% Appearance: SOLID MF: C10H15N5O10P2 MW: 427.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-Uridylic acid Order number: 212038 CAS: 58-97-9 Purity: 95% Appearance: SOLID MF: C9H13N2O9P MW: 324.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine, cyclic 3',5'-(hydrogen phosphate) Order number: 212039 CAS: 60-92-4 Purity: 99% Appearance: SOLID MF: C10H12N5O6P MW: 329.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ?-NADH Order number: 212040 CAS: 606-68-8 Purity: 98% Appearance: SOLID MF: C21H27N7Na2O14P2 MW: 709.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |