We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Guanosine 5'-(tetrahydrogen triphosphate), disodium salt Order number: 212041 CAS: 56001-37-7 Purity: 90% Appearance: SOLID MF: C10H14N5Na2O14P3 MW: 567.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 5'-Adenylic acid Order number: 212044 CAS: 61-19-8 Purity: 97% Appearance: SOLID MF: C10H14N5O7P MW: 347.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Riboflavin 5'-(dihydrogen phosphate), monosodium salt, dihydrate Order number: 212046 CAS: 6184-17-4 Purity: 73-79% Appearance: SOLID MF: C17H21N4Na2O10P MW: 518.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-Cytidylic acid Order number: 212047 CAS: 63-37-6 Purity: 95% Appearance: SOLID MF: C9H14N3O8P MW: 323.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Uridine 5'-(tetrahydrogen triphosphate) Order number: 212048 CAS: 63-39-8 Purity: ?98% Appearance: SOLID MF: C9H15N2O15P3 MW: 484.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: ?-Nicotinamide adenine dinucleotide lithium salt Order number: 212050 CAS: 64417-72-7 Purity: ?95% Appearance: n.a. MF: C21H28LiN7O14P2 MW: 671.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |