We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-Adenylic acid, 2'-deoxy- Order number: 212051 CAS: 653-63-4 Purity: 95% Appearance: SOLID MF: C10H14N5O6P MW: 331.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine5'-(trihydrogen diphosphate), 2'-deoxy-, disodium salt (9CI) Order number: 212056 CAS: 72003-83-9 Purity: n.a.% Appearance: n.a. MF: C10H13N5Na2O9P2 MW: 455.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Guanosine 5'-(trihydrogen diphosphate), disodium salt Order number: 212058 CAS: 7415-69-2 Purity: 90% Appearance: SOLID MF: C10H13N5Na2O11P2 MW: 487.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Thymidine5'-(trihydrogen diphosphate), trisodium salt (9CI) Order number: 212071 CAS: 95648-78-5 Purity: 90% Appearance: SOLID MF: C10H13N2Na3O11P2 MW: 468.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: ?-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate Order number: 212073 CAS: 1184-16-3 Purity: 93% Appearance: SOLID MF: C21H27N7NaO17P3 MW: 765.4 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite] Order number: 212077 CAS: 98796-51-1 Purity: 97% Appearance: SOLID MF: C40H49N4O8P MW: 744.8 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |