We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl] hydrogen phosphate Order number: 212104 CAS: 15839-70-0 Purity: 98% Appearance: SOLID MF: C16H25N5O15P2 MW: 589.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2 -O-Methyl-P-thiouridylyl-(3 ?5 )-2 -deoxyadenosine Order number: 212107 CAS: 475650-36-3 Purity: 98% Appearance: SOLID MF: C20H26N7O10PS MW: 587.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine 3'-CE phosphoramidite Order number: 212112 CAS: 142808-44-4 Purity: 97% Appearance: n.a. MF: C46H50F2N5O8P MW: 869.9 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: 3'-Phosphoadenosine 5'-phosphosulfate triethylammnonium salt Order number: 212115 CAS: 936827-87-1 Purity: n.a.% Appearance: n.a. MF: C16H30N6O13P2S MW: 608.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: UDP-D-glucuronide ammonium salt Order number: 212118 CAS: 43195-60-4 Purity: ?98% Appearance: n.a. MF: C15H25N3O18P2 MW: 597.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Sodium 5'-Inosinate hydrate(2:1:7) Order number: 212123 CAS: 849725-39-9 Purity: 98% Appearance: SOLID MF: C10H25N4Na2O15P MW: 518.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |