We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Uridine 5'-(trihydrogen diphosphate) sodium salt Order number: 212130 CAS: 1457-11-0 Purity: 97% Appearance: n.a. MF: C9H13N2NaO12P2 MW: 426.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Guanosine 5?-O-(2-Thiodiphosphate), Trilithium Salt Order number: 212134 CAS: 97952-36-8 Purity: n.a.% Appearance: n.a. MF: C10H12Li3N5O10P2S MW: 477.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Guanosine5'-phosphatedisodiumsalthydrate Order number: 212138 CAS: 146894-16-8 Purity: 97% Appearance: SOLID MF: C10H14N5Na2O9P MW: 425.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Flavinadeninedinucleotidedisodiumsalthydrate Order number: 212139 CAS: 1891059-93-0 Purity: 98% Appearance: SOLID MF: C27H33N9Na2O16P2 MW: 847.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Thymidine 5?-monophosphate p-nitrophenyl Order number: 212154 CAS: 98179-10-3 Purity: ?98 (HPLC)% Appearance: n.a. MF: C16H18N3NaO10P MW: 466.3 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2'-FLUORO-5'-O-DMT-2'-DEOXYINOSINE-3'-CE-PHOSPHORAMIDITE Order number: 212155 CAS: 2245842-16-2 Purity: 98% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |