We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: DMT-2'-O-propargyl-G(iBu)-CE Phosphoramidite Order number: 204783 CAS: n.a. Purity: 98% Appearance: solid MF: C47H56N7O9P MW: 893.98 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-2'-O-propargyl-C(Bz)-CE Phosphoramidite Order number: 204784 CAS: n.a. Purity: 98% Appearance: solid MF: C49H54N5O9P MW: 887.97 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: DMT-2'-O-propargyl-A(Ac)-CE Phosphoramidite Order number: 204785 CAS: n.a. Purity: 98% Appearance: solid MF: C45H52N7O8P MW: 849.93 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: 5-Me-DMT-2'-O-propargyl-U-CE Phosphoramidite Order number: 204786 CAS: n.a. Purity: 98% Appearance: solid MF: C43H51N4O9P MW: 798.87 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: 5-Me-DMT-2'-O-propargyl-C(Bz)-CE Phosphoramidite Order number: 204787 CAS: n.a. Purity: 98% Appearance: solid MF: C50H56N5O9P MW: 902.00 MP: n.a. oC Description: This is a useful building block in oligonucleotide synthesis on solid phase both for research and commercial drug development. |
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Product Name: dATP Order number: 204790 CAS: 54680-12-5 Purity: 98% Appearance: solid MF: C10H13N5Na3O12P3 MW: 557.13 MP: n.a. oC Description: dNTP and NTP are widely used in PCR, cRNA synthesis, RCA, MDA, DNA labeling and sequencing, in vitro transcription, etc. |