Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Nucleoside Phosphoramidites and Nucleotides
  • 2-Methylated Amino Acids

    Structure Details
    Product Name: (R)-alpha-Methyl-2-bromophenylalanine
    Order number: 204683
    CAS: 1212307-90-8
    Purity: >=95%
    Appearance: solid
    MF: C10H12BrNO2
    MW: 258.115
    MP: n.a. oC

    Description:
    This alpha-methylated amino acid is used to make the peptide bond more stable against enzymatic hydrolysis.
    Product Name: (S)-alpha-Methyl-3-bromophenylalanine
    Order number: 204684
    CAS: 1212117-73-1
    Purity: >=95%
    Appearance: solid
    MF: C10H12BrNO2
    MW: 258.115
    MP: n.a. oC

    Description:
    This alpha-methylated amino acid is used to make the peptide bond more stable against enzymatic hydrolysis.
    Product Name: (R)-alpha-Methyl-3-bromophenylalanine
    Order number: 204685
    CAS: 1212321-90-8
    Purity: >=95%
    Appearance: solid
    MF: C10H12BrNO2
    MW: 258.115
    MP: n.a. oC

    Description:
    This alpha-methylated amino acid is used to make the peptide bond more stable against enzymatic hydrolysis.
    Product Name: (S)-alpha-Methyl-4-bromophenylalanine
    Order number: 204686
    CAS: 747397-27-9
    Purity: >=95%
    Appearance: solid
    MF: C10H12BrNO2
    MW: 258.115
    MP: n.a. oC

    Description:
    This alpha-methylated amino acid is used to make the peptide bond more stable against enzymatic hydrolysis.
    Product Name: (R)-alpha-Methyl-4-bromophenylalanine
    Order number: 204687
    CAS: 752971-41-8
    Purity: >=95%
    Appearance: solid
    MF: C10H12BrNO2
    MW: 258.115
    MP: n.a. oC

    Description:
    This alpha-methylated amino acid is used to make the peptide bond more stable against enzymatic hydrolysis.
    Product Name: (S)-alpha-Methyl-3-Iodophenylalanine
    Order number: 204688
    CAS: 457653-01-9
    Purity: >=95%
    Appearance: solid
    MF: C10H12INO2
    MW: 305.115
    MP: n.a. oC

    Description:
    This alpha-methylated amino acid is used to make the peptide bond more stable against enzymatic hydrolysis.