We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 4-Amino-5-fluoro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Order number: 211716 CAS: 10356-76-0 Purity: 98% Appearance: SOLID MF: C9H12FN3O4 MW: 245.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ?,?-Methyleneguanosine 5'-triphosphate sodium salt Order number: 211717 CAS: 10470-57-2 Purity: ?95% Appearance: n.a. MF: C11H18N5NaO13P3 MW: 544.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 2'-Deoxycytidine-5'-monophosphoric acid Order number: 211718 CAS: 1032-65-1 Purity: 95% Appearance: SOLID MF: C9H14N3O7P MW: 307.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2'-Deoxy-5'-O-DMT-5-iodouridine Order number: 211719 CAS: 104375-88-4 Purity: 97% Appearance: SOLID MF: C30H29IN2O7 MW: 656.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 8-AZAADENOSINE Order number: 211720 CAS: 10299-44-2 Purity: 97% Appearance: SOLID MF: C9H12N6O4 MW: 268.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol Order number: 211721 CAS: 890-38-0 Purity: 98% Appearance: SOLID MF: C10H12N4O4 MW: 252.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |