We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT Order number: 211741 CAS: 103226-10-4 Purity: 97% Appearance: n.a. MF: C9H10FN2Na2O8P MW: 370.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 6-Iodo-uridine Order number: 211742 CAS: 105967-11-1 Purity: 95% Appearance: SOLID MF: C9H11IN2O6 MW: 370.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-O-Acetyl-3,5-bis-(4-chlorobenzoyl)-2-deoxy-D-ribose Order number: 211743 CAS: 1207459-15-1 Purity: n.a.% Appearance: WHITE POWDER MF: C21H18Cl2O7 MW: 453.3 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 9-(2-Deoxy-2-fluoroarabinofuranosyl)guanine Order number: 211744 CAS: 103884-98-6 Purity: n.a.% Appearance: WHITE POWDER MF: C10H12FN5O4 MW: 285.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]uridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Order number: 211745 CAS: 118362-03-1 Purity: 97% Appearance: SOLID MF: C45H61N4O9PSi MW: 861 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: 6-AMino-5-azacytidine Order number: 211746 CAS: 105331-00-8 Purity: 97% Appearance: SOLID MF: C8H13N5O5 MW: 259.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |