We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: adenosine5 -diphosphate,monosodiumsaltdihydrate Order number: 211747 CAS: 1172-42-5 Purity: 98% Appearance: n.a. MF: C10H14N5NaO10P2 MW: 449.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Order number: 211748 CAS: 110764-79-9 Purity: 98% Appearance: SOLID MF: C40H49N4O9P MW: 760.8 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: 7-Deaza-2'-C-ethynyladenosine Order number: 211749 CAS: 1044589-82-3 Purity: 98% Appearance: n.a. MF: C13H14N4O4 MW: 290.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-Methyl- Order number: 211750 CAS: 110764-74-4 Purity: 98% Appearance: SOLID MF: C38H37N3O8 MW: 663.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ADENOSINE 3'-PHOSPHATE 5'-PHOSPHOSULFATE LITHIUM Order number: 211751 CAS: 109434-21-1 Purity: n.a.% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 3',5'-Di-O-acetyl-5-broMo-2'-O-Methyluridine Order number: 211752 CAS: 1188522-81-7 Purity: 95% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |