We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: DMT-2?-O-Me-rG(ib) amidite Order number: 211807 CAS: 251647-55-9 Purity: 95% Appearance: YELLOW POWDER MF: C47H60N7O10P MW: 914 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
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Product Name: N6-BENZYLADENOSINE Order number: 211809 CAS: 4294-16-0 Purity: 98% Appearance: SOLID MF: C17H19N5O4 MW: 357.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-Chloro-3,5-di-O-toluoyl-2-deoxy-D-ribofuranose Order number: 211810 CAS: 3601-89-6 Purity: 90% Appearance: WHITE POWDER MF: C21H21ClO5 MW: 388.8 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 8-CHLOROADENOSINE Order number: 211811 CAS: 34408-14-5 Purity: 98% Appearance: SOLID MF: C10H12ClN5O4 MW: 301.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 8-HYDROXYGUANOSINE Order number: 211813 CAS: 3868-31-3 Purity: 98% Appearance: OFF-WHITE SOLID POWDER MF: C10H13N5O6 MW: 299.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: Adenylyl Imidodiphosphate Order number: 211814 CAS: 25612-73-1 Purity: ?93 (HPLC), powder% Appearance: n.a. MF: C10H15Li4N6O13P3 MW: 547.9 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |