We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N5-[(Methylamino)(methylimino)methyl]-L-ornithine Order number: 204398 CAS: 30344-00-4 Purity: >=95% Appearance: solid MF: C8H18N4O2 MW: 202.258 MP: n.a. oC Description: This amino acid once incorporated in peptide may enhance its cellular permeability. |
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Product Name: N5-[Bis(methylamino)methylene]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine Order number: 204399 CAS: 823780-66-1 Purity: >=95% Appearance: solid MF: C23H28N4O4 MW: 424.501 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. |
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Product Name: N5-[(Dimethylamino)iminomethyl]-L-ornithine Order number: 204400 CAS: 30315-93-6 Purity: >=95% Appearance: solid MF: C8H18N4O2 MW: 202.258 MP: n.a. oC Description: This amino acid once incorporated in peptide may enhance its cellular permeability. |
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Product Name: N5-[(Dimethylamino)iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine Order number: 204401 CAS: 268564-10-9 Purity: >=95% Appearance: solid MF: C23H28N4O4 MW: 424.501 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. |
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Product Name: (R)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanoic acid Order number: 204404 CAS: 292150-20-0 Purity: >=95% Appearance: solid MF: C20H20N2O5 MW: 368.389 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. |
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Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-6-heptenoic acid Order number: 204406 CAS: 1093645-21-6 Purity: >=95% Appearance: solid MF: C22H23NO4 MW: 365.429 MP: n.a. oC Description: The alkenyl side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process |