We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio- Order number: 211374 CAS: 13153-27-0 Purity: 99% Appearance: SOLID MF: C17H18N6O6S MW: 434.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Ribose, 2,3-O-(1-methylethylidene)- Order number: 211375 CAS: 13199-25-2 Purity: 95 GC% Appearance: COLOURLESSLIQUID MF: C8H14O5 MW: 190.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: Cytidine, 2-thio- Order number: 211376 CAS: 13239-97-9 Purity: ?98% Appearance: OFF-WHITE POWDER MF: C9H13N3O4S MW: 259.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, N-(2-phenylacetyl)- Order number: 211377 CAS: 132628-16-1 Purity: 98% Appearance: SOLID MF: C18H19N5O6 MW: 401.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 9H-Purine, 2,6-dichloro-9-?-D-ribofuranosyl- Order number: 211378 CAS: 13276-52-3 Purity: 97% Appearance: SOLID MF: C10H10Cl2N4O4 MW: 321.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Inosine, 2-chloro- (7CI,8CI,9CI) Order number: 211379 CAS: 13276-43-2 Purity: n.a.% Appearance: SOLID MF: C10H11ClN4O5 MW: 302.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |