We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N2-Isobutyryl-2'-O-Methyl-guanosine Order number: 211910 CAS: 63264-29-9 Purity: 98% Appearance: WHITE POWDER MF: C15H21N5O6 MW: 367.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-RIBOSE 1-PHOSPHATE, BISCYCLOHEXYLAMMONIUM SALT Order number: 211911 CAS: 58459-37-3 Purity: n.a.% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: CYTIDINE 5'-TRIPHOSPHATE DISODIUM Order number: 211912 CAS: 652154-13-7 Purity: n.a.% Appearance: n.a. MF: C9H18N3Na2O15P3 MW: 547.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 3',5'-DI-O-ACETYL-5-BROMO-2'-DEOXY-D-URIDINE Order number: 211913 CAS: 6161-23-5 Purity: 95% Appearance: SOLID MF: C13H15BrN2O7 MW: 391.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside Order number: 211914 CAS: 64363-77-5 Purity: 95% Appearance: LIQUID MF: C27H30O5 MW: 434.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: .alpha.-D-Arabinofuranoside, methyl Order number: 211915 CAS: 56607-40-0 Purity: n.a.% Appearance: LIQUID MF: C6H12O5 MW: 164.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |