We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-8-nonenoic acid Order number: 204407 CAS: 1262886-63-4 Purity: >=95% Appearance: solid MF: C24H27NO4 MW: 393.483 MP: n.a. oC Description: The alkenyl side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a ring-closure metathesis process |
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Product Name: N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino](methylimino)methyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine Order number: 204409 CAS: 1135616-49-7 Purity: >=95% Appearance: solid MF: C35H42N4O7S MW: 662.802 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used orthogonally to enhance peptide function/property. |
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Product Name: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-8-(tert-butoxy)-8-oxooctanoic acid Order number: 204410 CAS: 276869-41-1 Purity: >=95% Appearance: solid MF: C27H33NO6 MW: 467.562 MP: n.a. oC Description: Fmoc/Boc-protected solid-phase amenable steric amino acid is used orthogonally to enhance peptide function. |
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Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-Hexanedioic acid-6-(tert-butyll) ester Order number: 204411 CAS: 159751-47-0 Purity: >=95% Appearance: solid MF: C25H29NO6 MW: 439.508 MP: n.a. oC Description: Fmoc/Boc-protected solid-phase amenable steric amino acid is used orthogonally to enhance peptide function. |
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Product Name: (2S)-4-Azido-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-butanoic acid Order number: 204413 CAS: 942518-20-9 Purity: >=95% Appearance: solid MF: C19H18N4O4 MW: 366.377 MP: n.a. oC Description: The azido side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a click chemistry |
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Product Name: N6-Diazo-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-L-lysine Order number: 204415 CAS: 1050501-64-8 Purity: >=95% Appearance: solid MF: C22H24N4O4 MW: 408.458 MP: n.a. oC Description: The azido side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a click chemistry |