We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Uridine, 3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]- Order number: 211936 CAS: 69304-38-7 Purity: 95% Appearance: SOLID MF: C21H38N2O7Si2 MW: 486.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE Order number: 211937 CAS: 666848-11-9 Purity: 97% Appearance: SOLID MF: C15H26IN3O4Si MW: 467.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: URIDINE 5'-MONOPHOSPHATE DISODIUM SALT HYDRATE Order number: 211939 CAS: 681435-27-8 Purity: 97% Appearance: SOLID MF: C9H13N2Na2O10P MW: 386.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: B-NICOTINAMIDE ADENINE DINUCLEOTIDE*PHOS PHATE SODIU Order number: 211940 CAS: 698999-85-8 Purity: ?98 (HPLC)% Appearance: SOLID MF: C21H29N7NaO18P3 MW: 783.4 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 6-THIO-2'-DEOXYGUANOSINE Order number: 211941 CAS: 789-61-7 Purity: 98% Appearance: SOLID MF: C10H13N5O3S MW: 283.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Order number: 211944 CAS: 821794-92-7 Purity: 99% Appearance: SOLID MF: C18H19FN4O2 MW: 342.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |