We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine,N-benzoyl-2'-deoxy-, monohydrate (9CI) Order number: 212008 CAS: 305808-19-9 Purity: 98% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thymidine, 3'-deoxy- Order number: 212009 CAS: 3416-05-5 Purity: 97% Appearance: WHITESOLID POWDER MF: C10H14N2O4 MW: 226.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: L-Thymidine Order number: 212010 CAS: 3424-98-4 Purity: 98% Appearance: SOLID MF: C10H14N2O5 MW: 242.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine5'-(tetrahydrogen triphosphate), disodium salt, hydrate (8CI,9CI) Order number: 212011 CAS: 34369-07-8 Purity: 98% Appearance: WHITE POWDER MF: C10H16N5Na2O14P3 MW: 569.2 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 5'-Thymidylic acid, disodium salt Order number: 212012 CAS: 33430-62-5 Purity: 95% Appearance: SOLID MF: C10H13N2Na2O8P MW: 366.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine, 2-chloro-N-cyclopentyl- Order number: 212013 CAS: 37739-05-2 Purity: 98% Appearance: n.a. MF: C15H20ClN5O4 MW: 369.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |