Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

• 14 / 157

Structure	Details
	Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-7-azidoheptanoic acid Order number: 204416 CAS: 1191429-12-5 Purity: >=95% Appearance: solid MF: C23H26N4O4 MW: 422.485 MP: n.a. oC Description: The azido side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a click chemistry Login to check availability and price information.
	Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-8-azidooctanoic acid Order number: 204417 CAS: 1191429-14-7 Purity: >=95% Appearance: solid MF: C24H28N4O4 MW: 436.512 MP: n.a. oC Description: The azido side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a click chemistry Login to check availability and price information.
	Product Name: (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentynoic acid Order number: 204418 CAS: 1198791-65-9 Purity: >=95% Appearance: solid MF: C21H19NO4 MW: 349.386 MP: n.a. oC Description: The alkynyl side chain of this product can be tied (stapled) with another adjacent alkenyl side chain pre-existed on the peptide backbone via a click chemistry Login to check availability and price information.
	Product Name: N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysine Order number: 204419 CAS: 386213-32-7 Purity: >=95% Appearance: solid MF: C33H32N2O8 MW: 584.625 MP: n.a. oC Description: This is a valuable fluorescent to label peptide at N-terminal. Login to check availability and price information.
	Product Name: (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,2-dimethyl-1,3-Benzodioxole-5-propanoic acid Order number: 204420 CAS: 852288-18-7 Purity: >=95% Appearance: solid MF: C27H25NO6 MW: 459.498 MP: n.a. oC Description: Fmoc-protected solid-phase amenable amino acid is used to enhance peptide function/property. Login to check availability and price information.
	Product Name: 2'-O-(2-Methoxyethyl)-5-methylcytidine Order number: 204423 CAS: 244105-55-3 Purity: >=95% Appearance: solid MF: C13H21N3O6 MW: 315.326 MP: n.a. oC Description: This 2'-modified nucleoside is useful for biological and medicinal studies. Login to check availability and price information.

• 14 / 157