We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Guanosine 5'-(trihydrogen diphosphate), disodium salt Order number: 212058 CAS: 7415-69-2 Purity: 90% Appearance: SOLID MF: C10H13N5Na2O11P2 MW: 487.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- Order number: 212059 CAS: 81246-79-9 Purity: 97?contain4-5DCM?% Appearance: SOLID MF: C30H30N2O8 MW: 546.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)- Order number: 212060 CAS: 81246-83-5 Purity: 97% Appearance: WHITE POWDER MF: C35H37N5O8 MW: 655.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, N-benzoyl-2'-deoxy-2'-fluoro-2'-methyl-, 3',5'-dibenzoate,(2'R)- Order number: 212061 CAS: 817204-32-3 Purity: 97% Appearance: SOLID MF: C31H26FN3O7 MW: 571.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, 3'-deoxy- Order number: 212062 CAS: 73-03-0 Purity: 98% Appearance: SOLID MF: C10H13N5O3 MW: 251.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 2'-deoxy-2'-fluoro-2'-methyl-, 3',5'-dibenzoate, (2'R)- Order number: 212063 CAS: 863329-65-1 Purity: 98% Appearance: SOLID MF: C24H21FN2O7 MW: 468.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |