We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine, 2-fluoro-, 2',3',5'-triacetate Order number: 211408 CAS: 15811-32-2 Purity: 98% Appearance: SOLID MF: C16H18FN5O7 MW: 411.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, 2',3'-O-(1-methylethylidene)-, 5'-acetate Order number: 211409 CAS: 15888-38-7 Purity: 95% Appearance: SOLID MF: C15H19N5O5 MW: 349.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5'-deoxy- Order number: 211410 CAS: 15958-99-3 Purity: 95% Appearance: OFF-WHITE POWDER MF: C9H12N2O5 MW: 228.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 9H-Purin-6-amine, 2-fluoro-9-(2,3,5-tri-O-acetyl-?-D-arabinofuranosyl)- Order number: 211412 CAS: 161109-77-9 Purity: 95% Appearance: SOLID MF: C16H18FN5O7 MW: 411.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-, 2',3'-diacetate Order number: 211413 CAS: 162204-20-8 Purity: 97% Appearance: SOLID MF: C19H26FN3O8 MW: 443.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-?-D-ribofuranosyl- Order number: 211414 CAS: 16220-07-8 Purity: 98% Appearance: n.a. MF: C10H12N4O5 MW: 268.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |