We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: ?-D-Ribofuranuronamide, 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl- Order number: 211415 CAS: 163042-96-4 Purity: ?98(HPLC)% Appearance: SOLID MF: C18H18ClIN6O4 MW: 544.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 9H-Purin-2-amine, 6-chloro-9-(2,3,5-tri-O-acetyl-?-D-ribofuranosyl)- Order number: 211416 CAS: 16321-99-6 Purity: 98% Appearance: WHITE POWDER MF: C16H18ClN5O7 MW: 427.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]- (9CI) Order number: 211417 CAS: 163706-58-9 Purity: 97% Appearance: WHITE POWDER MF: C16H22F3N5O4S2 MW: 469.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, 2'-deoxy-, hydrate (1:1) Order number: 211418 CAS: 16373-93-6 Purity: 95% Appearance: SOLID MF: C10H15N5O4 MW: 269.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 5'-deoxy-5-fluoro-, 2',3'-diacetate Order number: 211419 CAS: 161599-46-8 Purity: 95% Appearance: SOLID MF: C13H16FN3O6 MW: 329.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, 2-methyl- Order number: 211421 CAS: 16526-56-0 Purity: n.a.% Appearance: n.a. MF: C11H15N5O4 MW: 281.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |