We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Thymidine, 3'-acetate Order number: 211455 CAS: 21090-30-2 Purity: 97% Appearance: SOLID MF: C12H16N2O6 MW: 284.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 3-methyl-, mono(methyl sulfate) (salt) (8CI,9CI) Order number: 211456 CAS: 21028-20-6 Purity: 98% Appearance: SOLID MF: C11H19N3O8S MW: 353.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 5-fluoro- Order number: 211457 CAS: 2341-22-2 Purity: 95% Appearance: SOLID MF: C9H12FN3O5 MW: 261.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2(1H)-Pyridinone, 4-hydroxy-1-?-D-ribofuranosyl- Order number: 211458 CAS: 23205-42-7 Purity: 97% Appearance: SOLID MF: C10H13NO6 MW: 243.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- Order number: 211459 CAS: 23669-79-6 Purity: 98% Appearance: SOLID MF: C30H30N2O7 MW: 530.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-?-D-erythro-pentofuranosyl)- Order number: 211460 CAS: 2353-33-5 Purity: 98% Appearance: WHITE POWDER MF: C8H12N4O4 MW: 228.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |