We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Thymidine, 5'-deoxy-5'-iodo- Order number: 211470 CAS: 25953-14-4 Purity: 95% Appearance: n.a. MF: C10H13IN2O4 MW: 352.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, 7,8-dihydro-8-thioxo- Order number: 211471 CAS: 26001-38-7 Purity: n.a.% Appearance: SOLID MF: C10H13N5O5S MW: 315.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2(1H)-Pyrimidinone, 4-amino-1-?-L-ribofuranosyl- Order number: 211472 CAS: 26524-60-7 Purity: 98% Appearance: WHITE POWDER MF: C9H13N3O5 MW: 243.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,4(1H,3H)-Pyrimidinedione, 1-?-L-ribofuranosyl- Order number: 211473 CAS: 26287-69-4 Purity: 98% Appearance: SOLID MF: C9H12N2O6 MW: 244.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 6H-Purin-6-one, 2-amino-1,9-dihydro-9-?-L-ribofuranosyl- Order number: 211474 CAS: 26578-09-6 Purity: 98% Appearance: OFF-WHITE SOLID POWDER MF: C10H13N5O5 MW: 283.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5-chloro- Order number: 211479 CAS: 2880-89-9 Purity: n.a.% Appearance: SOLID MF: C9H11ClN2O6 MW: 278.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |