We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diamine Order number: 204556 CAS: 18620-92-3 Purity: >=95% Appearance: solid MF: C6H7N5 MW: 149.157 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 1H-Pyrrolo[2,3-d]pyrimidine-2,4-(3H,7H)-dione Order number: 204558 CAS: 39929-79-8 Purity: >=95% Appearance: solid MF: C6H5N3O2 MW: 151.125 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidine Order number: 204559 CAS: 271-70-5 Purity: >=95% Appearance: solid MF: C6H5N3 MW: 119.127 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidin-2-amine Order number: 204560 CAS: 93366-88-2 Purity: >=95% Appearance: solid MF: C6H6N4 MW: 134.142 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 4-Amino-7H-pyrrolo[2,3-d] pyrimidin-2-ol Order number: 204561 CAS: 100047-45-8 Purity: >=95% Appearance: solid MF: C6H6N4O MW: 150.141 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 4-Methoxy-7H-pyrrolo[2,3-d] pyrimidine Order number: 204562 CAS: 4786-76-9 Purity: >=95% Appearance: solid MF: C7H7N3O MW: 149.153 MP: n.a. oC Description: Heterocycle and nucleoside building block. |