We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 9H-Purine, 2,6-dichloro-9-(2,3,5-tri-O-acetyl-?-D-ribofuranosyl)- Order number: 211488 CAS: 3056-18-6 Purity: 97% Appearance: SOLID MF: C16H16Cl2N4O7 MW: 447.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5'-deoxy-5-fluoro- Order number: 211492 CAS: 3094-09-5 Purity: 98% Appearance: SOLID MF: C9H11FN2O5 MW: 246.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ?-D-Glucopyranosiduronic acid, 4-(acetylamino)phenyl, methyl ester, 2,3,4-triacetate Order number: 211494 CAS: 30824-21-6 Purity: n.a.% Appearance: SOLID MF: C21H25NO11 MW: 467.4 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2,4(1H,3H)-Pyrimidinedione, 1-?-D-arabinofuranosyl- Order number: 211495 CAS: 3083-77-0 Purity: 98% Appearance: SOLID MF: C9H12N2O6 MW: 244.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 5-bromo- Order number: 211496 CAS: 3066-86-2 Purity: 95% Appearance: SOLID MF: C9H12BrN3O5 MW: 322.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,3-O-Isopropylidene-1-O-Methyl-D-Ribosic Acid Order number: 211497 CAS: 54622-95-6 Purity: 97% Appearance: SOLID MF: C9H14O6 MW: 218.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |