We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2'-O-Methyladenosine Order number: 211498 CAS: 2140-79-6 Purity: 98% Appearance: WHITE POWDER MF: C11H15N5O4 MW: 281.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 4-[2-[[6-Amino-9-(N-ethyl-?-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid Order number: 211499 CAS: 124182-57-6 Purity: ?98 (HPLC)% Appearance: n.a. MF: C23H29N7O6 MW: 499.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Bromo-7-?-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Order number: 211500 CAS: 21193-80-6 Purity: 97% Appearance: SOLID MF: C11H13BrN4O4 MW: 345.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-Deoxy-5-fluorocytidine Order number: 211501 CAS: 66335-38-4 Purity: 97% Appearance: SOLID MF: C9H12FN3O4 MW: 245.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Methylcytidine Order number: 211502 CAS: 2140-61-6 Purity: 97% Appearance: SOLID MF: C10H15N3O5 MW: 257.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenine 9-beta-D-arabinofuranoside Order number: 211503 CAS: 5536-17-4 Purity: 95% Appearance: WHITE POWDER MF: C10H13N5O5 MW: 283.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |