We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 9-beta-D-Ribofuranosyl-9H-purin-6-amine Order number: 211504 CAS: 58-61-7 Purity: 99% Appearance: WHITING MF: C10H13N5O4 MW: 267.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide Order number: 211505 CAS: 2627-69-2 Purity: ?98% Appearance: SOLID MF: C9H14N4O5 MW: 258.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 6-Chloropurine 9-?-D-ribofuranoside Order number: 211506 CAS: 5399-87-1 Purity: 98% Appearance: YELLOW POWDER MF: C10H11ClN4O4 MW: 286.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Bromo-2'-deoxyuridine Order number: 211508 CAS: 59-14-3 Purity: 98% Appearance: SOLID MF: C9H11BrN2O5 MW: 307.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 4-Amino-1-?-D-ribofuranosyl-2(1H)-pyrimidinone Order number: 211509 CAS: 65-46-3 Purity: 99% Appearance: WHITE POWDER MF: C9H13N3O5 MW: 243.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytosine ?-D-arabinofuranoside Order number: 211510 CAS: 147-94-4 Purity: 98% Appearance: SOLID MF: C9H13N3O5 MW: 243.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |