We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2'-Fluoro-2'-deoxyuridine Order number: 211518 CAS: 784-71-4 Purity: 98% Appearance: WHITE POWDER MF: C9H11FN2O5 MW: 246.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-Deoxyadenosine Order number: 211519 CAS: 958-09-8 Purity: 98% Appearance: WHITE POWDER MF: C10H13N5O3 MW: 251.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine Order number: 211521 CAS: 81246-82-4 Purity: 95% Appearance: SOLID MF: C38H35N5O7 MW: 673.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol Order number: 211522 CAS: 83-88-5 Purity: 98% Appearance: SOLID MF: C17H20N4O6 MW: 376.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2',3'-Dideoxyinosine Order number: 211523 CAS: 69655-05-6 Purity: ?98 (HPLC)% Appearance: WHITE POWDER MF: C10H12N4O3 MW: 236.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-Fluoro-2'-deoxyadenosine Order number: 211525 CAS: 64183-27-3 Purity: 98% Appearance: WHITE POWDER MF: C10H12FN5O3 MW: 269.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |